April Stempien-Otero, MD, FACC
Associate Professor
Associate Program Director for Research, Cardiology Fellowship
Craig Tall Family Endowed Chair in Heart Failure Research
Attending Physician, University of Washington Medical Center

Faculty Information


Dr. Stempien-Otero is the Craig Tall Family Endowed Professor in Heart Failure Research and a UW associate professor of medicine. As a practicing heart failure transplant cardiologist who has participated in multicenter clinical trials and undergone substantial additional training in basic science research, Dr. Stempien-Otero has developed the skills to bring bench to bedside studies to fruition.

Her lab is using both mouse and human models to understand the role of bone marrow derived cells in cardiac repair. These studies include a Phase 1 trial to evaluate the histologic effects of injection of bone marrow cells into patients undergoing left ventricular assist device as a bridge to cardiac transplantation. In addition, her lab is collecting cardiac tissue from humans undergoing left ventricular assist device placement or cardiac transplantation. These samples are used for histologic analysis and isolation of RNA from cell fractions.

Dr. Stempien-Otero earned her bachelor’s degree from Dartmouth College and her M.D. from the University of Connecticut’s School of Medicine. After being chief resident at the University of Virginia, she came to the UW for a cardiology fellowship and was chief fellow. She is board certified in internal medicine and cardiology. Among her honors, Dr. Stempien-Otero has been named a Best Doctor in America from 2002-present, received the Mentored Physician Scientist Award from the NIH and been named CME Teacher of the Year by the UW School of Medicine. Dr. Stempien-Otero's personal interests include cooking, soccer, trail running, and shellfish farming and gathering.

Education & Training: 
Fellowship in Cardiology
University of Washington
Seattle, WA
University of Virginia
Charlottesville, VA
University of Connecticut School of Medicine
Farmington, CT
Dartmouth College
Hanover, NH
CME Teacher of the Year, University of Washington School of Medicine
Vice President, Executive Board, American Heart Association, Metro King County
Mentored Physician Scientist Award, NIH
Best Doctors in America
ATVB Merit Award, American Heart Association Annual Meeting
Chief Fellow, University of Washington
Fellowship Award, American Heart Association, Washington Affiliate
Chief Resident, University of Virginia
Mailing Address: 
UW Research
South Lake Union Complex
850 Republican Street, Brotman 142
Box 358050
Seattle, WA 98109

Non-Clinical Administrative Support Contact:

Mary Ann Bonds



For appointments or other clinical matters, please contact the Heart Institute.

Research & Clinical Interests
Research Interests: 
  • Translational Research in End-stage Heart Failure
Clinical Interests: 
  • Congetive Heart Failure
  • Cardiac Transplantation
  • Heart Failure in Adult Congenital Heart Disease
  • Mechanical Circulatory Support