Catherine M. Otto, MD, FACC, FACP, FAHA
J. Ward Kennedy-Hamilton Endowed Chair in Cardiology
Director, Heart Valve Clinic
Attending Physician, University of Washington Medical Center

Faculty Information


Catherine Otto is the J. Ward Kennedy-Hamilton Endowed Chair in Cardiology, Professor of Medicine and Director of the Heart Valve Clinic at the University Of Washington School Of Medicine in Seattle, Washington. She is recognized internationally as an expert in the diagnosis and management of heart valve disease, Marfan syndrome and other inherited structural heart conditions. 

Dr. Otto’s research has transformed our understanding of calcific valve disease, showing that it may be amenable to medical therapy rather than being an inevitable consequence of aging. She is the author of several cardiology textbooks and cardiology editor-in-chief for the online medical textbook Up-to-Date. She currently serves as Editor in Chief of the journal Heart, and the Journal of British Cardiovascular Society, published by BMJ Publishing.

Dr. Otto's practice focuses on knowledge-based decision-making using established national guidelines for patient care and involving the patient actively in the decision process. 

Education & Training: 
Fellowship in Cardiology
University of Washington
Seattle, WA
Residency in Internal Medicine
The New York Hospital-Cornell Medical Center
New York, NY
University of Washington
Seattle, WA
Reed College
Portland, OR
Distinguished Scientist Award (Clinical Domain), American College of Cardiology
Honors, University of Washington School of Medicine
Mailing Address: 
University of Washington
1959 NE Pacific Street
Box 356422
Seattle, WA 98195-6422
Non-Clinical Administrative Support Contact:
Sally Habegger
For appointments or other clinical matters, please contact the Heart Institute.
Research & Clinical Interests
Research Interests: 
  • Calcific Aortic Valve Disease.
  • Validation of Noninvasive Measures of Disease Severity
  • Establishing the Cellular and Molecular Mechanisms of Valve Disease
  • Defining the Clinical Risk Factors Associated with Calcific Valve Disease
  • Aortic sclerosis
  • Marfan Syndrome: Prevention of Aortic Root Dilation
  • Bicuspid Aortic Valve Disease
  • Aortic Stenosis: Etiology and Prevention of Disease Progression
Clinical Interests: 
  • Aortic valve stenosis
  • Bicuspid aortic valve
  • Mitral regurgitation, mitral valve prolapse and stenosis
  • Aortic regurgitation
  • Marfan syndrome
  • Loey-Dietz syndrome
  • Cardiac involvement in systemic diseases and other inherited cardiac conditions