VA Puget Sound Health Care System
1660 S Columbian Way
Seattle, WA 98108-8280
The Yang lab is interested in modeling genetic and acquired cardiomyopathies (disease of the heart muscle) with patient-specific and/or gene-edited human induced pluripotent stem cells. By studying the mechanisms that lead to heart disease in a human model, we hope to develop novel therapies that will better translate clinically for patients with heart disease. Ongoing projects are focused on cardiomyopathies due to inflammation, diabetes, and MYH7 mutations.