Jeffrey L. Probstfield, MD, FACP, FACC, FESC
Professor
Medicine
Director, Clinical Trials Service Unit

Faculty Information

Biography

In 1995, the Clinical Trials Service Unit (CTSU) in the Division of Cardiology was founded by the current CTSU Director, Jeffrey Probstfield, M.D.  Dr. Probstfield brought his years of experience in clinical trials training to direct the CTSU to this day. Since its more humble beginnings, the CTSU has grown to occupy 4800 square feet and has 12 offices and 2 large conference areas. In addition, Kelley Branch, MD, MSc joined CTSU in 2012 as the Associate Director.

The focus of activities in the unit has been to identify, support (manage and monitor) clinical centers for large multi-center clinical trials for national and international multi-center clinical trials.  Each project or trial is directed by a faculty-level individual and managed and supported by a lead project coordinator.  Depending on the trial, the responsibilities of the project coordinators may involve any or all of the following: gathering regulatory documents, developing budgets, site identification and vetting, training, evaluation of site data reports, monitoring of recruitment, adherence to protocol, follow-up of cohort, monitoring visits to clinical sites, primary communication and resource for clinic sites, development of tools, forms and worksheets.  

The CTSU also works closely with several coordinating centers in conducting large scale trials such as the recently completed AIM-HIGH, ORIGIN, and the ACCORD trials. Over 20 trials have been supported by CTSU which spans from the RESOLVD trial to the most recently completed ACCORD and AIM-HIGH trials.  

Education & Training: 
Graduate School
University of Minnesota, Department of Pharmacology
Minneapolis, MN
1976
Trainee in Clinical Pharmacology
University of Minnesota Hospitals
Minneapolis, MN
1973
Fellowship
University of Minnesota Hospitals
Minneapolis, MN
1971
MD
University of Washington School of Medicine
Seattle, WA
1967
Internship
Hennepin County General Hospital
Minneapolis, MN
1968
BA
Pacific Lutheran University
Tacoma, WA
1963
Honors: 
US Investigators' Committee, CHARM
US Coordinator: INTERHEART, OASIS7/CURRENT, COMPASS, REWIND Trials
PI AIM-HIGH, AIMHIGH COORDINATING CENTER Trials
PI FLAT-SUGAR
Teaching: Biostat 524: Design of Clinical Studies (School of Public Health Course on Clinical Trials)