This is unpublished

Jeffrey L.
Probstfield
MD
FACP
FACC
FESC

Faculty
Pinned
Academic
Professor Emeritus, Medicine
Professional
Director, Clinical Trials Service Unit
Sites of Practice
UW Medical Center - Montlake

CONTACTS

Mailing Address:
University of Washington Medical Center,
1959 NE Pacific Street,
Box 356422,
Seattle, WA 98195-6422

Non-Clinical Administrative Support:
UW Cardiology

Clinical Contacts:
For appointments or other clinical matters, please contact the Heart Institute.

About

In 1995, the Clinical Trials Service Unit (CTSU) in the Division of Cardiology was founded by the current CTSU Director, Jeffrey Probstfield, M.D.  Dr. Probstfield brought his years of experience in clinical trials training to direct the CTSU to this day. Since its more humble beginnings, the CTSU has grown to occupy 4800 square feet and has 12 offices and 2 large conference areas. In addition, Kelley Branch, MD, MSc joined CTSU in 2012 as the Associate Director.

The focus of activities in the unit has been to identify, support (manage and monitor) clinical centers for large multi-center clinical trials for national and international multi-center clinical trials.  Each project or trial is directed by a faculty-level individual and managed and supported by a lead project coordinator.  Depending on the trial, the responsibilities of the project coordinators may involve any or all of the following: gathering regulatory documents, developing budgets, site identification and vetting, training, evaluation of site data reports, monitoring of recruitment, adherence to protocol, follow-up of cohort, monitoring visits to clinical sites, primary communication and resource for clinic sites, development of tools, forms and worksheets.  

The CTSU also works closely with several coordinating centers in conducting large scale trials such as the recently completed AIM-HIGH, ORIGIN, and the ACCORD trials. Over 20 trials have been supported by CTSU which spans from the RESOLVD trial to the most recently completed ACCORD and AIM-HIGH trials.  

Education & Training 

Graduate School

University of Minnesota, Department of Pharmacology

Minneapolis, MN

1976

Trainee in Clinical Pharmacology

University of Minnesota Hospitals

Minneapolis, MN

1973

Fellowship

University of Minnesota Hospitals

Minneapolis, MN

1971

MD

University of Washington School of Medicine

Seattle, WA

1967

Internship

Hennepin County General Hospital

Minneapolis, MN

1968

BA

Pacific Lutheran University

Tacoma, WA

1963

Honors

US Investigators' Committee, CHARM

US Coordinator: INTERHEART, OASIS7/CURRENT, COMPASS, REWIND Trials

PI AIM-HIGH, AIMHIGH COORDINATING CENTER Trials

PI FLAT-SUGAR

Teaching: Biostat 524: Design of Clinical Studies (School of Public Health Course on Clinical Trials)

Research Interests

  • Type II Diabetes Prevention and Treatment
  • Dyslipidemia
  • Re-Vascularization
  • Hypertension
  • Cardiac Disease (Acute Coronary Syndrome)
  • Chronic Heart Failure

Clinical Interests

  • Treatment of Hyperlipidemia
  • Treatment of High Blood Pressure

Publications